THE ROLE OF “MICROBIAL FACTOR” IN THE DEVELOPMENT OF ADENOMYOSIS (review)

Endometriosis is a multifactorial disease that affects mainly women of reproductive age. The exact pathogenesis this still mystery. analysis modern etiology concepts and mechanisms adenomyosis development were carried out. review includes data from foreign articles published in the PubMed, UpToDate, eLibrary databases over past ten years. A number works presenting studies uterus microbiota its influence on analyzed. possibilities cultural molecular genetic diagnostic methods, particular 16S rRNA, studying state uterine cavity are described. paradigm progression provides for presence endometrium bacterial contamination which, turn, trigger cell modifications activating vicious circle pathology.